Masterclass on Pleiotropic role of IL-5 across diseases

IL-5 directly involves and affects several target cells, including eosinophils and B cells, inducing cell proliferation, survival and differentiation, making it a key factor in the inflammatory process in asthma, CRSwNP, EGPA and HES. Understanding this inflammatory phenomenon and its specific treatment options is essential for the management of patients and their comorbidities.
This webinar comprehensively address the full complexity of IL-5 and its mechanism of action.

Learning Objectives:

• To develop the concept of immune response and its mechanisms
• To put the focus in IL-5 as a modulator of response
• To understand the biological effects of IL-5 and the broader role beyond eosinophilic inflammation
• To link Type 2 inflammation with respiratory diseases To interpret the mechanism of action of biologics

LECTURE 1: What do we talk about when we talk about IL-5?

• Past and present of our knowledge about IL-5
• IL-5 as a modulator of our acquired immune response
• Eosinophils and Type 2 inflammation

LECTURE 2: IL-5: the multi-causal nexus

• Respiratory field – Asthma, and CRSwNP

LECTURE 3: IL-5: A Key Target in Type 2 Disease

• Understanding the mechanism of action
• Severe/refractory asthma – Putting the focus on decreasing the burden of the disease
• Severe/refractory CRSwNP
• IL-5 vs. IL-5R
• Future perspectives